Practitioner Resources: Dermatology-Focused

Information Regarding Drug Usage – Links to Abstracts and Research Articles

5-Fluorouracil

Topical 5% 5-fluorouracil cream in the treatment of plantar warts: a prospective, randomized, and controlled clinical study.

Treatment of verruca plantaris with a combination of topical fluorouracil and salicylic acid.

Aluminum chloride

Treatment of primary hyperhidrosis.

Azelaic acid

Modern approach to topical treatment of aging skin.

Benzoyl Peroxide

Benzoyl peroxide in the treatment of decubitus ulcers.

Utility of topical benzoyl peroxide for prevention of surgical skin wound infection.

Cantharidin

Cantharidin revisited: a blistering defense of an ancient medicine.

Childhood molluscum contagiosum: experience with cantharidin therapy in 300 patients.

Cholestyramine

Cholestyramine ointment in the treatment of perianal skin irritation following ileoanal anastomosis.

Cholestyramine ointment to treat buttocks rash and anal excoriation in an infant.

Coal tar

No increased risk of cancer after coal tar treatment in patients with psoriasis or eczema.

Dehydroepiandrosterone (DHEA)

Modern approach to topical treatment of aging skin.

Dimethylaminoethanol

The antiwrinkle effect of topical concentrated 2-dimethylaminoethanol involves a vacuolar cytopathology.

The role of dimethylaminoethanol in cosmetic dermatology.

Glycolic acid

Comparison of topical therapy for striae alba (20% glycolic acid/0.05% tretinoin versus 20% glycolic acid/10% L-ascorbic acid).

Safety and efficacy of 4% hydroquinone combined with 10% glycolic acid, antioxidants, and sunscreen in thetreatment of melasma.

The use of chemical peelings in the treatment of different cutaneous hyperpigmentations.

Glycopyrrolate

Craniofacial hyperhidrosis successfully treated with topical glycopyrrolate.

Glycopyrrolate 1% Cream.

The beneficial effect of topical glycopyrrolate in a patient with neuropathic lower extremity pain.

ABHR Gel in the Treatment of Nausea and Vomiting in the Hospice Patient.

Hydroquinone

A double-blind randomized trial of 5% ascorbic acid vs. 4% hydroquinone in melasma.

Modern approach to topical treatment of aging skin.

Safety and efficacy of 4% hydroquinone combined with 10% glycolic acid, antioxidants, and sunscreen in thetreatment of melasma.

Imiquimod

An open, nonrandomized, comparative study of imiquimod 5% cream versus 10% potassium hydroxide solution in the treatment of molluscum contagiosum.

An open, randomized, comparative clinical and histological study of imiquimod 5% cream versus 10% potassium hydroxide solution in the treatment of molluscum contagiosum.

Kojic acid

Modern approach to topical treatment of aging skin.

The use of chemical peelings in the treatment of different cutaneous hyperpigmentations.

Methotrexate

Management of psoriasis vulgaris with methotrexate 0.25% in a hydrophilic gel: a placebo-controlled, double-blind study.

Topical 0.25% methotrexate gel in a hydrogel base for palmoplantar psoriasis.

Topical methotrexate delivered by iontophoresis in the treatment of recalcitrant psoriais–a case report.

N-acetylcysteine

Topical N-acetylcysteine for lamellar ichthyosis.

Topical use of N-acetylcysteine for reduction of skin reaction to radiation therapy.

NADH

Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome.

Topical application of NADH for the treatment of rosacea and contact dermatitis.

Niacinamide

Nicotinic acid/niacinamide and the skin.

Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin.

Nicotinamide

Moisturizing effects of topical nicotinamide on atopic dry skin.

Pharmacologic doses of nicotinamide in the treatment of inflammatory skin conditions: a review.

Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris.

Phenol

Phenol and menthol in the treatment of chronic skin lesions following mustard gas exposure.

Phenylalanine

Decreased phenylalanine uptake and turnover in patients with vitiligo.

Oral and topical L-phenylalanine, clobetasol propionate, and UVA/sunlight–a new study for the treatment of vitiligo.

Treatment of vitiligo with oral and topical phenylalanine: 6 years of experience.

Phytonadione

The effects of topical application of phytonadione, retinol and vitamins C and E on infraorbital dark circles and wrinkles of the lower eyelids.

Potassium Hydroxide

An open, nonrandomized, comparative study of imiquimod 5% cream versus 10% potassium hydroxide solution in the treatment of molluscum contagiosum.

An open, randomized, comparative clinical and histological study of imiquimod 5% cream versus 10% potassium hydroxide solution in the treatment of molluscum contagiosum.

Evaluation of the effectiveness of 5% potassium hydroxide for the treatment of molluscum contagiosum.

Treatment of molluscum contagiosum with potassium hydroxide: a clinical approach in 35 children.

Pramoxine

A pramoxine-based anti-itch lotion is more effective than a control lotion for the treatment of uremic pruritus in adult hemodialysis patients.

Potassium Hydroxide

An open, nonrandomized, comparative study of imiquimod 5% cream versus 10% potassium hydroxide solution in the treatment of molluscum contagiosum.

An open, randomized, comparative clinical and histological study of imiquimod 5% cream versus 10% potassium hydroxide solution in the treatment of molluscum contagiosum.

Evaluation of the effectiveness of 5% potassium hydroxide for the treatment of molluscum contagiosum.

Treatment of molluscum contagiosum with potassium hydroxide: a clinical approach in 35 children.

Pramoxine

A pramoxine-based anti-itch lotion is more effective than a control lotion for the treatment of uremic pruritus in adult hemodialysis patients.

Propantheline bromide

Propantheline bromide in the management of hyperhidrosis associated with spinal cord injury.

Pseudocatalase

In vivo and in vitro evidence for hydrogen peroxide (H2O2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase.

Melanocytes are not absent in lesional skin of long duration vitiligo.

Successful treatment of oxidative stress in vitiligo.

Treatment of vitiligo with a topical application of pseudocatalase and calcium in combination with short-term UVB exposure: a case study on 33 patients.

Pyrithione zinc

Does tachyphylaxis occur in long-term management of scalp seborrheic dermatitis with pyrithione zinc-based treatments?

Retinoic acid

Comparison of topical therapy for striae alba (20% glycolic acid/0.05% tretinoin versus 20% glycolic acid/10% L-ascorbic acid).

Topical tretinoin (retinoic acid) improves early stretch marks.

Topical tretinoin 0.1% for pregnancy-related abdominal striae: an open-label, multicenter, prospective study.

Retinol

The effects of topical application of phytonadione, retinol and vitamins C and E on infraorbital dark circles and wrinkles of the lower eyelids.

Salicylic Acid

Combination urea and salicylic acid ointment nail avulsion in nondystrophic nails: a follow-up observation.

The EVERT (effective verruca treatments) trial protocol: a randomised controlled trial to evaluate cryotherapy versus salicylic acid for the treatment of verrucae.

Topical tacrolimus ointment combined with 6% salicylic acid gel for plaque psoriasis treatment.

Treatment of verruca plantaris with a combination of topical fluorouracil and salicylic acid.

Sodium Salicylate

Treatment of plantar verrucae using 2% sodium salicylate iontophoresis.

Spironolactone

Comparison of the efficacy of 5% topical spironolactone gel and placebo in the treatment of mild and moderate acne vulgaris: a randomized controlled trial.

Topical spironolactone reduces sebum secretion rates in young adults.

Squaric acid

Squaric acid immunotherapy for warts in children.

Squaric acid dibutylester

Contact immunotherapy with squaric acid dibutylester for the treatment of recalcitrant warts.

Squaric acid immunotherapy for warts in children.

Use of squaric acid dibutylester (SADBE) for cutaneous warts in children.

Sucralfate

Natural history of late radiation proctosigmoiditis treated with topical sucralfate suspension.

Topical sucralfate in the management of peristomal skin disease: an open study.

Topical use of Sucralfate Cream in second and third degree burns.

Tacrolimus

Topical tacrolimus ointment combined with 6% salicylic acid gel for plaque psoriasis treatment.

Tamoxifen

Topical tamoxifen–a potential therapeutic regime in treating excessive dermal scarring?

Tazarotene

Palliative treatment of fingernail lichen planus.

Trichloroacetic acid

The use of chemical peelings in the treatment of different cutaneous hyperpigmentations.

Urea

A comparative evaluation of combination therapy of fluconazole 1%and urea 40% compared with fluconazole 1% alone in a nail lacquer for treatment of onychomycosis: therapeutic trial.

Combination of fluconazole and urea in a nail lacquer for treating onychomycosis.

Combination urea and salicylic acid ointment nail avulsion in nondystrophic nails: a follow-up observation.

Fungal nail infections: diagnosis and management.

Nail avulsion: Indications and methods (surgical nail avulsion).

The use of 40% urea cream in the treatment of moccasin tinea pedis.

Urea ointment in the nonsurgical avulsion of nail dystrophies–a reappraisal.

Urea plasters alternative to surgery for nail removal.

Urea ointment in the nonsurgical avulsion of nail dystrophies–a reappraisal.