Practitioner Resources: Circulation Focused

Information Regarding Drug Usage – Links to Abstracts and Research Articles

Clonidine

Topical Gel to Treat Diabetic Neuropathy Proves Successful in Phase 2.

Diltiazem

A comparative study on in vitro and in vivo effects of topical vasodilators in human internal mammary, radial artery and great saphenous vein.

General – Ace Inhibitors

Angiotensin converting enzyme inhibitors or DuP753 prevent neointimal formation following balloon injury with single topical or multiple systemic application.

Isosorbide Dinitrate

Improvement of walking distance in patients with intermittent claudication by chronic local therapy with isosorbide dinitrate ointment.

Isosorbide dinitrate ointment in the long-term treatment of intermittent claudication [article in Italian].

Nicardipine

Effect of topical vasodilators on gastroepiploic artery graft.

Nifedipine

Intranasal delivery of cardiovascular agents: an innovative approach to cardiovascular pharmacotherapy.

Evaluation of the method for nifedipine administration for a rapid onset of clinical effect: a clinical study in normal volunteers.

Nitroglycerin/Glyceryl Trinitrate

Nonsurgical treatment of chronic anal fissure: nitroglycerin and dilatation versus nifedipine and botulinum toxin.

Safety and efficacy of new glyceryl trinitrate suppository formula: first double blind placebo-controlled clinical trial.

The management of patients with primary chronic anal fissure: a position paper.

Propanolol

Intranasal delivery of cardiovascular agents: an innovative approach to cardiovascular pharmacotherapy.

Evaluation of Skin Permeation of β-Blockers for Topical Drug Delivery.